DataBase of CpG islands and Analytical Tool (DBCAT) is developed in order to recognize comprehensive mehtylation profiles of DNA alteration in human cancer.
DBCAT is an online methylation analytical tool composed of three parts: a CpG Island Finder, a genome query browser and an analytical tool for methylation microarray data. The analytical tool can analyze raw data generated from scanners and search genes with methylated regions which could affect gene expression regulation.
DBCAT not only identifies the regions of methylation but also searches the database to pick up genes with methylated regions of functional meanings.
Currently we use Agilent and Illumina microarray to perform our analysis.
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